I started prescribing isotretinoin (then called Accutane) when it was first approved for use in 1982. Since then, there has been no time during my career when I have not had patients taking the drug. Isotretinoin has revolutionized the treatment of acne and is responsible for the fact that we see far fewer cases of severe disfiguring cystic acne today than we did prior to its approval.
I would like to share some of my observations over the past 32 years of prescribing this drug.
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